Cloning and functional characterization of porcine Sox6
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منابع مشابه
The Effect of Endurance Activity on Expression of sox6 Gene of Left Ventricle in Male Wistar Rat
Background & Aims: The expression of myocardium gene can be affected by endurance activity; besides, sox6 transcription factor influences its formation. This study aimed to investigate the effect of 14 weeks of endurance activity on expression of sox6 gene of left ventricle in male Wistar rats. Methods: Forteen rats were housed under the controlled conditions and after adjusting with endurance ...
متن کاملcDNA cloning of the Sry-related gene Sox6 from rat with tissue-specific expression.
A cDNA encoding rat homologue of the previously characterized mouse Sox6 was isolated by a polymerase chain reaction (PCR) cloning strategy. Comparison of this eDNA with homologous mouse, human and rainbow trout cDNA exhibited an overall amino acid sequence identity of 99.6, 89.3 and 76.3% respectively. The leucine-zipper and HMG-box motif were almost completely conserved between these homologu...
متن کاملHuman Cancer Biology Characterization of Tumor-Suppressive Function of SOX6 in Human Esophageal Squamous Cell Carcinoma
Purpose: By using cDNA microarray analysis, we identified a transcriptional factor, SOX6, was frequently downregulated in esophageal squamous cell carcinoma (ESCC). The aim of this study is to investigate the role of SOX6 in human esophageal cancer development, and to examine the prevalence and clinical significance of SOX6 downregulation in ESCC. Experimental Design: Expressions of SOX6 mRNA i...
متن کاملBacterial Expression and Functional Characterization of A Naturally Occurring Exon6-less Preprochymosin cDNA
Chymosin (Rennin EC 3.4.23.4), an aspartyl proteinase, is the major proteolytic enzyme in the fourthstomach of the unweaned calf, and it is formed by proteolytic activation of its zymogene, prochymosin.Following the cloning of synthesized cDNAs on mRNA pools extracted from the mucosa of the calf fourthstomach, we have identified an alternatively spliced form of preprochymosin ...
متن کاملCharacterization of tumor-suppressive function of SOX6 in human esophageal squamous cell carcinoma.
PURPOSE By using cDNA microarray analysis, we identified a transcriptional factor, SOX6, was frequently downregulated in esophageal squamous cell carcinoma (ESCC). The aim of this study is to investigate the role of SOX6 in human esophageal cancer development, and to examine the prevalence and clinical significance of SOX6 downregulation in ESCC. EXPERIMENTAL DESIGN Expressions of SOX6 mRNA i...
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تاریخ انتشار 2015